Advanced Health Assessment Practice Exam

What anatomical regions are most commonly affected by squamous cell carcinoma?

1. Trunk and legs

2. Hands and head

3. Back and neck

4. Feet and nails

The correct answer is: Hands and head

Squamous cell carcinoma (SCC) most commonly affects areas of the skin that are frequently exposed to the sun, as well as regions where there may be a higher concentration of keratinocytes. The hands and head are particularly susceptible due to their direct exposure to ultraviolet (UV) radiation, which is a significant risk factor for developing skin cancers including SCC. The head, specifically the face, ears, and scalp, is often exposed to sunlight, making it a common site for the development of these malignant lesions. The hands also experience considerable sun exposure, especially since they are often left uncovered during outdoor activities. Thus, these anatomical regions are the most regularly impacted by squamous cell carcinoma due to their anatomical characteristics and environmental exposure, aligning well with the known risk factors associated with the disease. In contrast, the trunk and legs may have some risk due to sun exposure, but they are generally less frequently affected compared to the more exposed areas of the hands and head. The back and neck can also develop SCC, but they are not as common as the face and hands. Lastly, the feet and nails are not typical sites for squamous cell carcinoma, as these areas are less exposed to UV light. Therefore, the option emphasizing the hands and head accurately