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Which finding in the skin assessment of an adult client might raise suspicion of malignancy?

  1. Flat lesions with uniform color

  2. Asymmetrical lesions with irregular borders

  3. Raised lesions in a clustered configuration

  4. Multiple macules of consistent size

The correct answer is: Asymmetrical lesions with irregular borders

Asymmetrical lesions with irregular borders are typically characteristic of potential malignancies, particularly concerning skin cancers like melanoma. The asymmetry in shape suggests that the lesion may not be developing uniformly, which is a key feature assessed during skin examinations. Additionally, irregular borders indicate that the edges of the lesion are not well-defined, which can be a sign of uncontrolled cell growth associated with cancerous changes. In contrast, flat lesions with uniform color, raised lesions in a clustered configuration, and multiple macules of consistent size generally present as lesser concerns. Uniformity in color and symmetry typically indicates benign conditions, while clustered elevations could represent common dermatological issues such as infections or benign neoplasms rather than malignancy. Consistent size in multiple macules also suggests a stable and likely non-cancerous condition. Hence, the asymmetry and irregularity found in option B raise significant concern for malignancy.