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Which skin cancer is characterized by a pearly border with a central ulcer?

  1. Squamous Cell Carcinoma

  2. Basal Cell Carcinoma

  3. Melanoma

  4. Actinic Keratosis

The correct answer is: Basal Cell Carcinoma

Basal Cell Carcinoma (BCC) is the skin cancer characterized by a pearly border with a central ulcer. This lesion often appears on sun-exposed areas of the skin, such as the face and neck, and is known for its slow growth and low potential for metastasis. The pearly appearance of the border comes from the presence of nests of basaloid cells that can be observed microscopically. As BCC often develops in areas of skin damage related to UV exposure, recognizing its distinct clinical features, like the central ulcer and shiny appearance of the perimeter, is essential for early diagnosis and treatment. In contrast, other skin cancers present with different characteristics. Squamous Cell Carcinoma typically appears as a firm, red nodule or a flat lesion with a scaly, crusted surface but does not exhibit the same pearly appearance or central ulceration. Melanoma arises from melanocytes and often manifests as a dark mole with irregular borders and color variation, lacking the distinct features of BCC. Actinic Keratosis is a precancerous condition that usually presents as dry, scaly patches, which are also visually different from the characteristics of BCC. Understanding these differences is crucial for accurate identification and management of